Tubeless Product Families

Learn more about Totally Tubeless

Why Totally Tubeless

Through the use of “totally tubeless” shell vial and well plate cell cultures, incubation time can be reduced to 24-72 hours for many viruses. This falls within the recommended window for antiviral treatment, improving patient care and preventing the unnecessary use of antibiotics.

MixedCells and D^3™ Fluorescent Staining Kits

MixedCells and D³ Fluorescent Staining Kits allow laboratories to isolate multiple viruses simultaneously and also enable laboratories to reduce the number of tests that are referred to outside laboratories, capturing revenue and further reducing turnaound time.

Find out more about Totally Tubeless and Diagnostic Hybrids MixedCells™ and D^3® Fluorescent Staining Kits

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TotallyTubeless

an information resource provided by Diagnostic Hybrids

Totally Tubeless for Respiratory

R-Mix^™ and R-Mix Too^™

R-Mix ReadyCells^®

Identify seven major respiratory viruses in 15 minutes from direct patient specimen or incubated tissue cultures. Results of early detection (many results in 24 hours and all results in less than 48 hours from collection to result) are essential for specific patient therapy decisions. The D³ Ultra DFA Respiratory Virus Screening & ID Kit and the new D³ Duet DFA Respiratory Virus Screening Kits can rule in or rule out all seven major pathogens or identify any one of seven viruses using highly sensitive and specific reagents in a single 15 minute incubation step.
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Totally Tubeless for Herpesviruses

H&V-Mix

Hs27 ReadyCells

Patients with Herpes family (HSV, CMV, VZV) virus infections may be mildly to seriously ill. Differentiation and rapid detection of these viruses from lesions and non-lesion sources can be critical to patient management, treatment and reducing the risk of spread of virus from one individual to another. Diagnostic HYBRIDS' cell and monoclonal antibody systems are optimized for sensitive, specific and rapid detection as well as ease of laboratory testing. read more >>

Totally Tubeless for Enterovirus

Super E-Mix

Super E-Mix ReadyCells

Rapid isolation and identification of Enterovirus infections is essential for proper patient management. Diagnostic Hybridshas used its MixedCells™ technology to combine an engineered BGMK cell line with hDAF (human Decay Acceleration Factor, a cellular receptor for multiple Enteroviruses) with A549 cells to allow a broad range of Enterovirus isolates to grow in a reduced time frame compared to traditional tube culture isolation. Positive results are generally evident in one to three days after inoculation. read more >>

Totally Tubeless for Herpes Simplex

ELVIS^® HSV

The Enzyme Linked Virus Inducible System (ELVIS^®) is a complete system for the isolation and detection of Herpes simplex virus (HSV). The key to this system is the genetically modified baby hamster kidney cells (BHK). The transgenic BHK cells have been altered to include a HSV- specific promoter and a LacZ reporter gene. The two genes work in tandem to allow for detection of HSV by an enzyme-based histochemical reaction in 16 hours. The HSV positive cells form a blue precipitate when reacted with a chromogenic substrate. Due to the sensitivity of this system both positive and negative cultures can be reported in 16 hours. read more >>

Diagnostic Hybrids MixedCells^™ and D^3® Fluorescent Staining Kits

As part of its “totally tubeless” cell culture offering, Diagnostic HYBRIDS provides MixedCells – co-cultivated cell lines in the same shell vial or plate well, optimized for viral culture. These mixed cell substrates allow laboratories to isolate multiple viruses simultaneously, making it easier to detect co-infections in addition to the other benefits of “totally tubeless” cell cultures. MixedCells are also optimized for use with Diagnostic HYBRIDS’ patented D³ line of fluorescent staining kits for virus identification. Because these testing systems operate on the same principles, laboratory staff can easily be cross-trained to perform new tests.